Component.cmp

    <aura:registerEvent name="CRMAppEvent" type="c:CRMAppEvent"/>

Controller.js

        var compEvent = $A.get("e.c:CRMAppEvent"); 
        compEvent.setParams({"type" : response})
        compEvent.fire();

Are you receiving cannot read property ‘setParams’ of undefined after assigning an event?

This indicates that $A.get(“e.c:CRMAppEvent”) cannot find the event and any reference to setParams method or any properties of the event would eventually be undefined.
To fix this you need to set your application event access to global

CRMAppEvent.evt

<aura:event type="APPLICATION" description="This is the generic Application Event" access="global">
    <aura:attribute name="type" type="String"/>
</aura:event>

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